James Conway
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Phone (412) 383-9847
Fax (412) 648-8998
University of Pittsburgh
2047 Biomedical Science Tower 3
James Conway
Department of Structural Biology
Visit Conway's lab website
Education & Training
Undergraduate
Massey University, Palmerstrom, North New Zealand
B.S. 1985 in Physics
Graduate
Massey University, Palmerston North New Zealand
Ph.D. 1989 in Biophysics
Postgraduate
National Institues of Health
Bethesda, MD 1990 - 1996
Awards & Honors
1986 Fibrous Proteins Merit Award, Massey University
1997 Special Achievement Award, NIAMS/NIH, In recognition and appreciation of special achievement
1998 Group Merit Award, NIAMS/NIH, In recognition of pioneering contributions to image processing, advancing the resolution attainable in biological electron microscopy
Representative Publications
Lee H, Brendle SA, Bywaters SM, Guan J, Ashley RE, Yoder JD, Makhov AM, Conway JF, Christensen ND & Hafenstein S. A CryoEM study identifies the complete H16.V5 epitope and reveals global conformational changes initiated by binding of the neutralizing antibody fragment. J Virol 89, 1428-1438, 2015
Shingler KL, Cifuente JO, Ashley RE, Makhov AM, Conway JF & Hafenstein S. The enterovirus 71 procapsid binds neutralizing antibodies and rescues virus infection in vitro. J Virol 89, 1900-1908, 2015.
Sattar S, Bennett NJ, Wen WX, Guthrie JM, Blackwell LF, Conway JF & Rakonjac J. Ff-nano, short functionalized nanorods derived from Ff (f1, fd or M13) filamentous bacteriophage. Frontiers in Microbiology (Virology) 6, 316, 2015.
Guan J, Bywaters SM, Brendle SA, Lee H, Ashley RE, Makhov AM, Conway JF, Christensen ND & Hafenstein S. Structural comparison of four different antibodies interacting with human papillomavirus 16 and mechanisms of neutralization. Virology 483, 253-263, 2015.
Tandon R, Mocarski ES and Conway JF. The A, B, Cs of herpesvirus capsids. Viruses 7, 899-914. 2015.
Active Grants
Direct Electron Detecting (DED) Camer
04/01/15 – 03/31/16
National Institutes of Health
S10
Structure and Function of the Herpesvirus Capsid
08/15/11 – 07/31/20
National Institutes of Health
R01
Structural Determinants of Amelogenin Function in Regulating Enamel Formation
09/01/12 – 08/31/17
National Institutes of Health
R01
Inborn Errors of Long Chain Fat Metabolism
07/01/07 – 03/31/16
National Institutes of Health
R01
Roles of Cytomegalovirus Proteins pp150 and pUL96 in Virus Maturation
11/01/14 – 10/31/19
National Institutes of Health
R01